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个人简介
Dr. Aparicio’s research program encompasses the fields of cancer genomics, cancer evolution, single cell biology, mouse genetic models, high throughput screens, small molecule chemical probe development and translational breast cancer research. His work on the molecular taxonomy of breast cancer led to identification of new genes that could change the way breast cancer is diagnosed, and form the basis of next-generation treatments. This discovery was preceded by another breakthrough in decoding the genetic makeup of the most-deadly form of breast cancer, known as triple negative subtype (TNBC). Dr. Aparicio is also working to develop quantitative measures of clonal fitness in patients, including methods for single cell genome sequencing and PDX models of human cancer. He collaborates widely with other groups, with current projects including the genomic and biochemical analysis of lymphoma, ovarian cancer, and several rare pediatric cancers.
研究兴趣
论文共 316 篇作者统计合作学者相似作者
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Alvin Wei Tian Ng, Dylan Peter McClurg, Ben Wesley, Shahriar A Zamani, Emily Black,Ahmad Miremadi,Olivier Giger,Rogier Ten Hoopen,Ginny Devonshire,Aisling M Redmond,Nicola Grehan,Sriganesh Jammula,
Nature communicationsno. 1 (2024): 4074-4074
Cold Spring Harbor perspectives in medicine (2024)
Alvin Wei Tian Ng,Dylan Peter McClurg, Ben Wesley, Shahriar A Zamani, Emily Black,Ahmad Miremadi,Olivier Giger,Rogier Ten Hoopen,Ginny Devonshire,Aisling M Redmond,Nicola Grehan,Sriganesh Jammula,
Nature communicationsno. 1 (2024): 4533-4533
Marc J. Williams, Michael UJ Oliphant, Vinci Au, Cathy Liu, Caroline Baril, Ciara O’Flanagan,Daniel Lai,Sean Beatty, Michael Van Vliet, Jacky CH Yiu, Lauren O’Connor, Walter L Goh,
biorxiv(2024)
Elena Zaikova,Brian Y C Cheng, Viviana Cerda,Esther Kong,Daniel Lai,Amy Lum,Cherie Bates,Wendie den Brok,Takako Kono, Sylvie Bourque,Angela Chan, Xioalan Feng,
NPJ breast cancerno. 1 (2024): 3-3
Eric Lee, Dongkyu Lee, Wayne Fan,Andrew Lytle, Yuxiang Fu,David W. Scott,Christian Steidl,Samuel Aparicio,Andrew Roth
Cancer Researchno. 7_Supplement (2023): 5523-5523
Research Square (Research Square) (2023)
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