A FLIM photosensitizer: Targeting “Affinal” suborganelles to accelerate cancer cell oxidative stress and apoptosis

Jinsong Li,Junjun Wang, Yuanfang Zhu,Xiaojiao Zhu,Zhipeng Yu,Jie Zhang,Lianke Wang,Jianhua Yu,Zhenbang Liu,Hongping Zhou

Journal of Photochemistry and Photobiology A: Chemistry（2022）

引用 1|浏览2

暂无评分

摘要

An amphiphilic small-molecule PS (CMOOH) anchoring on the two original and derived suborganelles (ER and LDs) were prepared, producing ROS for causing ERS and lipophagy to accelerate the apoptosis of cancer cells, of which apoptotic mechanism was observed by CLSM/FLIM.

查看译文

关键词

Photosensitizer,Fluorescence lifetime imaging,Multi-photon,Oxidative damage,Sub-organelles targeting

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要