Abstract 14470: Novel Autophagy Mechanisms of NP-6A4 Protection in Heart Disease Induced by Untreated Obesity

Asma Boukhalfa,Anthony M Belenchia, Vincent De Marco,Pei Liu,Brian P. Mooney, Alexander Mehm,Yinian Tang,Lauren Ling,Madhavi P. Gavini,Howard H. Chen,Lakshmi Pulakat

Circulation（2021）

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Introduction & Hypothesis: Untreated obesity induces insulin resistance and heart disease affecting 42% of the US population. Autophagy, a conserved homeostatic process for cellular quality control...

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