Novel antidepressant-like properties of the fullerenol in an LPS-induced depressive mouse model

Anqi Kong,Tianyao Liu,Shilong Deng,Shiyao Xu,Yi Luo,Jianghui Li,Zhulin Du,Liuyongwei Wang,Xingshun Xu,Xiaotang Fan

International Immunopharmacology（2023）

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摘要

•Fullerenol alleviates the depression-like behavior induced by LPS administration in mice.•Fullerenol pretreatment prevents LPS-induced neuroinflammatory response in mouse hippocampus.•Fullerenol rescues the inhibited hippocampal neurogenesis of the LPS-treated mice.

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关键词

LPS,Depression,Fullerenol,Hippocampus,Neuroinflammation

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