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个人简介
The Getz laboratory is focused on cancer genome analysis, which includes two major steps: (i) Characterization – cataloging of all genomic events and the mechanisms that created them during the clonal evolution of cancer (starting from normal cells and progressing to premalignancy, primary cancer, and emergence of resistance), comparing events at the DNA, RNA, and protein levels between one or more tumor and normal samples from an individual patient; and (ii) Interpretation – analysis of the characterization data across a cohort of patients with the aim of identifying the alterations in genes and pathways that drive cancer progression, drive resistance, or increase its risk as well as identifying molecular subtypes of the disease, their markers, and relationship to clinical variables. Recently, the Getz lab is also studying the tumor and its immune microenvironment using both bulk and single-cell RNA-sequencing (RNA-seq) data. In addition to developing tools for high throughput analysis of cancer data and experimentally testing the findings, the Getz lab develops computer platforms that enable largescale analytics and visualization.
研究兴趣
论文共 790 篇作者统计合作学者相似作者
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Ferran Fece de la Cruz,Andreas Varkaris,Elizabeth E. Martin, Bryanna L. Norden, Nicholas Chevalier, Allison M. Kehlmann,Ignaty Leshchiner,Haley Barnes, Sara Ehnstrom, Parasvi Patel, Janice S. Kim,Haley Ellis,
Cancer Researchno. 7_Supplement (2024)
Nolan Priedigkeit, Alinés Lebrón-Torres, Janny Liao,Jean-Baptiste Alberge,Stefania Morganti,Jakob Weiss,Jorge Gomez Tejeda Zanudo,Albert Grinshpun,Melissa Hughes,Karla Helvie, Kerry Sendrick, Kyleen Nguyen,
Cancer Researchno. 9_Supplement (2024): GS03-09
Clinical Cancer Research (2024)
Andreas Varkaris,Ferran Fece de la Cruz,Elizabeth Martin, Bryanna Nordern, Nicholas Chevalier,Ignaty Leshchiner, Anastasia Stavridi, Janice Kim, Alkistis Papatheodoridi,Hakan Gunaydin,Brian Danysh,Laxmi Parida,
Cancer Researchno. 9_Supplement (2024): GS03-10
Andreas Varkaris,Ferran Fece de la Cruz,Elizabeth E. Martin, Bryanna L. Norden, Nicholas Chevalier, Allison M. Kehlmann,Ignaty Leshchiner,Haley Barnes, Sara Ehnstrom, Anastasia-Maria Stavridi,Xin Yuan, Janice S. Kim,
Anirban Das, Nicholas R. Fernandez, Adrian Levine,Vanessa Bianchi,Lucie K. Stengs,Jiil Chung,Logine Negm, Jose Rafael Dimayacyac, Yuan Chang,Liana Nobre,Ayse B. Ercan, Santiago Sanchez-Ramirez,
CANCER DISCOVERYno. 2 (2024): 258-273
Heather Parsons, Conor Messer,Katheryn Santos,Jakob Weiss, David Merrell,Brian Danysh,Melissa Hughes, Greg Kirkner,Ashka Patel,Julian Hess, Kerry Sendrick,Chip Stewart,
crossref(2024)
Siwei Chen,Laurent C. Francioli,Julia K. Goodrich,Ryan L. Collins,Masahiro Kanai,Qingbo Wang,Jessica Alfoldi, Nicholas A. Watts, Christopher Vittal,Laura D. Gauthier,Timothy Poterba,Michael W. Wilson,
NATUREno. 7993 (2024)
Siwei Chen,Laurent C. Francioli,Julia K. Goodrich,Ryan L. Collins,Masahiro Kanai,Qingbo Wang, Jessica Alfoeldi, Nicholas A. Watts, Christopher Vittal,Laura D. Gauthier,Timothy Poterba,Michael W. Wilson,
NATURE (2024)
Omar Nadeem,Michelle P Aranha,Robert Redd, Michael Timonian, Sophie Magidson,Elizabeth D Lightbody,Jean-Baptiste Alberge,Luca Bertamini,Ankit K Dutta,Habib El-Khoury,Mark Bustoros,Jacob P Laubach,
medRxiv : the preprint server for health sciences (2024)
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