John W. Rooney, Ph.D., J.D.
Biography
John did his undergraduate work in Molecular Biology at UC Berkeley, then went on to obtain his PhD in Genetics at Harvard. After a postodoctoral fellowship as a Cancer Research Institute fellowship recipient, he worked for three biotech companies. His focus of research throughout his fifteen years of study has been the molecular biology of the immune system.
John was a semester associate at Fletcher Allen Health Care in the Offices of Compliance, General Counsel, and Risk Management. John then returned to research as a one year Research Associate at Dartmouth College. For the last several years, he has been an Associate Professor (Adjunct) at various local colleges (Hesser College, Manchester Community College, Franklin Pierce University, NH Technical Institute) in Departments including Liberal Art, Legal Studies, Math and Sciences, and Chemisty and Biological Sciences. He also teaches on-line.
John recently passed both the Massachusetts State Bar Exam and the United States Patent and Trademark Office Exam for Registration for Practice. He is awaiting his licensure. His goal is to become a patent attorney.
Education
J.D., Vermont Law School, 2008
Intellectual Property Summer Institute Certificate, Advanced Licensing Institute Certificate, Franklin Pierce Law Center, 2006
Ph.D., Genetics, Harvard University, 1995
A.B., Molecular Biology, University of California, Berkeley, 1987
Publications
Postel, E. H., Berberich, S. J., Rooney, J. W., and Kaetzel, D. M. (2000). Human NM23/Nucleoside Diphosphate Kinase regulates gene expression through DNA binding to nuclease-hypersensitive transcriptional elements. J. Bioenergetics and Biomembranes 32(3): 277-284.
Rooney, J. W., Postel, E. H., and Calame, K. L. (1999). Proc. 3rd Intern. Congr. Genet. Biochem. Physiol. Nm23/Nucleoside Diphosphate Kinase. University of Bordeaux2, France, 20-22. September 1999, Absh. P15.
Ho, I.-C., Kim, John H.-I., Rooney, J. W., Spiegelman, B. M., and Glimcher, L. H.(1998). A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis. Proc. Natl. Acad. Sci. USA 95, 15537-15541.
Ho, I.-C., Hodge, M. R., Rooney, J. W., and Glimcher, L. H. (1996). The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85, 973-983.
Rooney, J. W. (1995). Regulation of the Interleukin-2 and Interleukin-4 genes in T helper 1 and T helper 2 cell clones. Doctoral Thesis, Harvard, Dept of Genetics.
Rooney, J. W., Sun, Y.-L., Glimcher, L. H., and Hoey, T. (1995). Novel NF-AT sites that mediate activation of the IL-2 promoter in response to T cell receptor stimulation. Mol. Cell. Biol. 15, 6299-6310.
Rooney, J. W., Hoey, T., and Glimcher, L. H. (1995). Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity 2, 473-483.
Rooney, J. W., Hodge, M. R., and Glimcher, L. H. (1995). The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites which bind at least two distinct factors. J. Immunol. 154, 6397-6405.
Rooney, J. W., Hodge, M. R., McCaffrey, P. G., Rao, A., and Glimcher, L. H. (1994). A common factor regulates both Th1 and Th2 specific cytokine gene expression. EMBO J. 13, 625-633.
Reimold, A. M., Kara, C. J., Rooney, J. W., and Glimcher, L. H. (1993). Transforming Growth Factor Beta-1 Repression of the HLA-DRalpha gene is mediated by conserved proximal promoter elements. J. Immunol. 151, 4173-4182
Eisenmann, D. M., Arndt, K. M., Ricupero, S. L., Rooney, J. W., and Winston, F. (1992). SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae. Genes & Dev. 6, 1319-1331
Miller, C. L., Feldhaus, A. L., Rooney, J. W., Rhodes, L. D., Sibley, C. H., and Singh, H. (1991). Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation. Mol. Cell. Biol. 11, 4885-4894.
Rooney, J. W., DuBois, P., and Sibley, C. H. (1991). Cross-linking of surface IgM activates NF-kappa B in B lymphocyte. Eur. J. Immunol. 21, 2993-2998.
Bomstzyk, K., Rooney, J. W., Twasaki, T., Rachie, N. A., Dower, S. K., and Sibley, C. H. (1991). Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C. Cell Regulation 2, 329-335.
Bomsztyk, K., Toivola, B., Emery, D. W., Rooney, J. W., Dower, S. K., Rachie, N. A., and Sibley, C. H. (1990). Role of cAMP in interleukin-1-induced kappa light chain gene expression in murine B cell line. J. Biol. Chem. 265, 9413-9417.
Rooney, J. W., Emery, D. W., and Sibley, C. H. (1990). 1.3E2, a variant of the B lymphoma 70Z/3, defective in activation of NF-kappa B and OTF-2. Immunogenetics 31, 73-78.
Rooney, J. W., Emery, D. W., and Sibley, C. H. (1990). Slow response variant of the B lymphoma 70Z/3 defective in activation in LPS activation of NF-kappaB. Immunogenetics 31, 65-72.
Emery, D. W., Rooney, J. W., and Sibley, C. H. (1989). A gamma interferon-unresponsive variant of cell line, 70Z/3, IFN-4, can be partially rescued by phorbol myristate acetate. Mol. Cell. Biol. 9, 5231-5233.